MEETING No. 17, HELD ON FEBRUARY 17th, 2000, SAN PIO X PRIVATE HOSPITAL, MILANO

Case 2
Case 3
Case 4
Case 5
Case 6

Case 1

"THYROID MASS"
F. FEDELI - La Spezia Hospital
(Photographs by dr. A. Faravelli)

Clinical history: 41y.o. woman presents with a 10 cm. mass which surround completely the thyroid (pict. 1); no FNA of the lesion is performed and the mass is surgically removed.
Microscopic description: the neoplasia is mainly on the outer surface of the thyroid from where it infiltrates the parenchyma (pict. 2).
The lesion has mainly epithelioid features with clear cells (pict. 3) - (pict. 4), squamous-like cells (pict. 5) - (pict. 6) and more undifferentiated areas with markedly atypical cells in a fibrous stroma (pict. 7) - (pict. 8).
The clear cells are negative with immunohistochemical staining with antisera for CD5.
In some of the sections in the peri-capsular region, rests of normal thymus (pict. 9) - (pict. 10) are noted.
Mitotic count is low and there is neoplastic vascular invasion.

Diagnosis

pict. 1	pict. 2
pict. 3	pict. 4
pict. 5	pict. 6
pict. 7	pict. 8
pict. 9	pict. 10

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