MEETING No. 17, HELD ON FEBRUARY 17th, 2000, SAN PIO X PRIVATE HOSPITAL, MILANO

Case 1
Case 2
Case 3
Case 4
Case 5

Case 6

"VULVAR PEDUNCOLATED LESION"
S. RAO - S. Pio X Private Hospital - Milano
(Photographs by dr. S. Rao)

Clinical history: a 52y.o. woman presents with occasional metrorrhagia and a peduncolated lesion is removed from the vulva.
Macroscopic description: A 2.5x7x1 cm, soft, elastic lesion (pict. 1).
Microscopic description: the lesion consists of medium and small vessels proliferation in a loose, myxoid stroma (pict. 2) - (pict. 3) - (pict. 4); the medium sized vessels have thickened wall.
The stromal cellular component consists of spindled or star-like cells with regular nuclei and central nucleoli (pict. 5); the cells are positive with immunohistochemical staining for alfa-Actin (pict. 6) and Desmin and are negative for protein S-100.
Occasional giant cells (pict. 7) and remnants of glands lined by cuboidal cells with regular nuclei (pict. 8) are noted .
Proliferation index is low.

Diagnosis

pict. 1	pict. 2
pict. 3	pict. 4
pict. 5	pict. 6
pict. 7	pict. 8

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