MEETING No. 29, CAMAIORE (LUCCA), MARCH 17th, 2001

Case 1
Case 2
Case 3
Case 4
Case 5
Case 6
Case 7

Case 4

"THYROID NODULE"
J. BRUNO - Camaiore Hospital
(pict. by dr. Faravelli)

Clinical history: a 79y.o. woman with no previous clinical history presents with a “toxic goitre”.
During surgery for thyroidectomy the surgeon requests a frozen section but it is not performed because there is no evidence of macroscopically suspicious lesions and because of the presence of calcified nodules.
Macroscopic description: a multi-nodular thyroid is observed, with the largest nodule, measuring 6 cm in diameter, in the right lobe. Microscopic description: The right nodule consists of cords of clear cells, sometimes with granular cytoplasm, round nuclei and prominent nucleoli; the lesion is infiltrating the surrounding tissue ( (pict. 1) - (pict. 2) - (pict. 3)).
Necrosis and haemorrage are present ( (pict. 4)), with haemosiderin deposits ( (pict. 5)).
Immunohistochemical staining for thyroglobulin ( (pict. 6)) is negative.

Diagnosis

pict. 1	pict. 2
pict. 3	pict. 4
pict. 5	pict. 6

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