MEETING No.41, APRIL 10th, 2002, FATEBENEFRATELLI HOSPITAL, MILANO

Case 1
Case 2
Case 3
Case 4
Case 5
Case 6

Case 4


"NEOPLASIA OF THE VULVA"
E. CASELLI - Melloni Hospital - Milano
(pict. by dr. Caselli)

Clinical history: a 27y.o. woman presents to the gynaecologist for the appearance of a nodule,superior portion of the vulva great lip. The clinical suspicion is of a Nuck cyst.
Macroscopical description: 5 cm, yellowish, elastic and semisolid mass with multi-lobulated borders (pict. 1 - pict. 2).
Microscopical description: the tumor consists of a spindled cells component (pict. 3 - pict. 4) with high mitotic index (pict. 5) and an epithelioid, tubular-glandular component (pict. 6 - pict. 7 - pict. 8) with intra-luminal PAS positive mucus production (pict. 9).
The epithelioid cells are positive with immunohistochemical staining for Cytokeratin (pict. 10) and focally for Vimentin (pict. 11).

Diagnosis

pict. 1	pict. 2
pict. 3	pict. 4
pict. 5	pict. 6
pict. 7	pict. 8
pict. 9	pict. 10
pict. 11

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