MEETING No. 49 HELD ON JANUARY 15th AT THE SAN PIO X PRIVATE HOSPITAL, MILAN

Case 1
Case 2
Case 3
Case 4

Case 1


"PIGMENTED LESION "
E. SCHIAFFINO – San Carlo Hospital - Milano
(pict. by dr. Crippa)

Clinical history: a 39y.o. man presents with a recently appeared and rapidly growing, pigmented lesion on the cheek. Macroscopical description: a 1.2x1x0.4 cm skin ellipse with thickened dermis. Microscopical description: in the dermis there is a proliferation of atypical, pleomorphic and scarcely cohesive cells, occasionally forming nests (pict. 1 - pict. 2 - pict. 3 - pict. 4 - pict. 5).
The cells infiltrate the reticular dermis but do not involve the epidermis (pict. 6 - pict. 7).
The mitotic and proliferation indexes are low. The neoplastic cells are positive with immunohistochemical staining for S100 (pict. 8 - pict. 9) and focally for HMB45.

Diagnosis

pict. 1	pict. 2
pict. 3	pict. 4
pict. 5	pict. 6
pict. 7	pict. 8
pict. 9

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